LISBON 15th International Conference on Bioscience, Biotechnology & Biomedical Engineering: LB3E-27

Call for papers/Topics

All Abstracts, Reviews, short articles, Full articles, Posters are welcomed related with any of the following research fields:

Foundational & Independent Topics

These topics represent the core scientific, technological, and engineering principles unique to each specific discipline.

1. Biosciences (The Scientific Foundation)

The fundamental study of living organisms, their molecular mechanisms, and their environments.

• Molecular and Cell Biology: Cellular architecture, organelle function, membrane dynamics, and metabolic pathways (cellular respiration, photosynthesis).

• Genetics and Molecular Inheritance: Mendelian genetics, chromosome mechanics, DNA replication, transcription, translation, and epigenetic modifications.

• Organismal Anatomy and Physiology: The structural layout and systemic functioning of human, animal, and plant systems.

• Microbiology and Virology: The biology of bacteria, archaea, fungi, viruses, and prions, including microbial pathogenesis and ecology.

2. Biotechnology (The Technological Application)

The use of cellular and biomolecular processes to develop technologies and products that improve human life and planetary health.

• Genetic Engineering and Molecular Cloning: Recombinant DNA technology, vector design, gene synthesis, and precision editing tools like CRISPR-Cas systems.

• Bioprocess and Fermentation Technology: Upstream processing, media optimization, bioreactor design, kinetics of microbial growth, and downstream purification (chromatography, filtration).

• Industrial and Environmental Biotechnology: Microbial synthesis of biofuels, bioplastics, bioremediation of environmental pollutants, and industrial enzyme production.

• Agricultural Biotechnology: Development of transgenic crops, pest resistance, drought tolerance, and molecular marker-assisted breeding.

3. Biomedical Engineering (The Engineering Architecture)

The application of engineering principles and design concepts to medicine and biology for healthcare purposes.

• Biomaterials and Tissue Engineering: Biocompatibility testing, biodegradable scaffolds, synthetic and natural polymers, and stem cell differentiation for organ regeneration.

• Biomedical Instrumentation and Sensors: Design of diagnostic devices, biosensors (glucose monitors, gas sensors), amplifiers, and medical signal processing (ECG, EEG).

• Biomechanics and Rehabilitation Engineering: Musculoskeletal mechanics, fluid dynamics of blood flow (hemodynamics), prosthetics, orthotics, and wearable robotic exoskeletons.

• Medical Imaging and Radiation Biophysics: Physics and engineering principles behind MRI, CT scans, ultrasound, X-ray imaging, and image reconstruction algorithms.

Interrelated & Integrated Topics

These fields represent the powerful multi-disciplinary overlaps where basic bioscience, technological scaling, and physical engineering converge.

1. Advanced Biomanufacturing and Synthetic Biology

The ultimate convergence where bioscience provides the genetic parts, biotechnology scales the living systems, and engineering optimizes the production platform.

• Synthetic Genomics and Metabolic Engineering: Writing entirely new genetic code to construct artificial metabolic pathways inside cells, transforming them into cellular factories.

• Cell-Free Biomanufacturing: Removing the metabolic machinery from the cell envelope to conduct complex biochemical synthesis in vitro, eliminating the constraints of cell survival.

• Scale-Up Engineering of Biologics: Merging bioprocess technology with mechanical engineering to scale up the production of monoclonal antibodies and viral vectors from benchtop to industrial volumes.

2. Genomic Medicine and Personalized Healthcare

The intersection where molecular bioscience discoveries are translated into targeted biological therapies and delivered via engineered medical systems.

• Pharmacogenomics and Targeted Drug Delivery: Using genetic profiling to predict patient drug responses, combined with engineered nanocarriers (liposomes, polymeric nanoparticles) to drop therapies directly into target tissues.

• Gene and Cell Therapies: Modifying a patient's own cells outside the body to fight disease (such as CAR-T cell therapy) and utilizing engineered viral or non-viral vectors for in vivo gene correction.

• Companion Diagnostics (CDx): Developing integrated bio-assays and hardware devices that determine the exact suitability of a specific biologic treatment for an individual patient.

3. Bio-Digital Convergence and Computational Medicine

The integration of data engineering, biological systems, and hardware to model, analyze, and interface with living systems.

• Bioinformatics and Structural Proteomics: Applying advanced computing and machine learning (such as deep learning protein folding models) to biological sequence data to predict 3D macromolecular structures.

• Systems Biology and In Silico Modeling: Building mathematical, computer-based simulations of complete cellular networks or whole-organ physiology to predict how they react to drugs or diseases.

• Brain-Computer Interfaces (BCIs) and Neural Engineering: High-level intersection of neurobiology and electrical engineering, creating direct communication pathways between the human nervous system and electronic computational devices.

4. Regenerative Medicine and Organs-on-Chips

The blending of cell biology, biomaterial scaffolding, and microfluidic engineering to replace or model human tissues.

• Microfluidic Organs-on-Chips: Creating microfabricated bio-chips that mimic the microarchitecture and physiological response of entire human organs (e.g., lung-on-a-chip) for high-throughput drug testing.

• 3D Bioprinting of Vascularized Tissues: Using additive manufacturing principles to deposit living cells layer-by-layer alongside artificial blood vessel networks to build functional, transplantable tissues.

• In Situ Tissue Regeneration: Engineering smart biomaterials that, when implanted, recruit the body's own native stem cells to the site of injury to jumpstart structural healing